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  • Engine Exhaust Valve-SOHC, Eng Code: AFC, 12 Valves

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    Barrett’s oesophagus may be the precursor of all oesophageal adenocarcinomas

    To cite: Curtius K, Rubenstein JH, Chak A, et al. Gut 2021;70:1435-1440.

    Read the full article here: link
    Objective: Barrett’s oesophagus (BE) is a known precursor to oesophageal adenocarcinoma (OAC) but current clinical data have not been consolidated to address whether BE is the origin of all incident OAC, which would reinforce evidence for BE screening efforts. We aimed to answer whether all expected prevalent BE, diagnosed and undiagnosed, could account for all incident OACs in the US cancer registry data.

    Conclusion: There are likely few additional OAC cases arising in the US population outside those expected from individuals with BE. Effective screening of high-risk patients could capture the majority of population destined for OAC progression and potentially decrease mortality through early detection and curative removal of small (pre)cancers during surveillance.

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